European Journal of Cardiovascular Medicine

Purpose: The purpose of this study was to determine the demographic and clinical characteristics of patients who had pancreaticoduodenectomy as an indication of pancreatic cancer. Methodology: This prospective observational study aimed to investigate the demographic and clinical characteristics of individuals who presented with pancreatic cancer and underwent pancreaticoduodenectomy. A cohort of 50 adult patients who were hospitalized in the Department of General Surgery Medical College Trivandrum and diagnosed with pancreatic or peri-ampullary cancer and subsequently received curative resection within the study period were included in the study. Results: Out of the total 50 study subjects, the majority of them were females, 27 (54% females), with a male-to-female ratio of 1.1:1. The majority of the participants were between the ages of 46 and 59 (44%) and 60 and older (34%). The majority of the study participants exhibit jaundice, accounting for 29 (58%). Diabetes mellitus was the most prevalent, being present in 12 patients (24%). The majority of the study participants were diagnosed with carcinoma of the head of the pancreas; 52% had periampullary carcinoma detected in 48%. A total of 25 patients had pylorus-preserving pancreaticoduodenectomy (PPPD), while another 25 study subjects underwent Classical Whipple's Resection. Conclusion: The study revealed that the incidence of pancreatic cancer was higher in females than males. The incidence is higher in the elderly population.