European Journal of Cardiovascular Medicine

Background: Stroke is the second leading cause of death worldwide and is defined as a sudden onset of neurological deficit that is attributable to a focal neurological cause. Several risk factors are attributable to the etiopathogenesis of stroke, among which hypertension, diabetes, dyslipidemia, lifestyle changes are modifiable. Hypertriglyceridemia is a risk factor for stroke because of its prothrombotic nature. Aim: The present study was to assess the correlation of serum triglycerides and TG/high-density lipoprotein ratio to the severity of stroke. Methodology: The present study is a prospective hospital-based study of 100 patients who attended the government general hospital between Dec 2017 to Oct 2019 and diagnosed as ischemic stroke based on clinical, imaging, and laboratory findings. Data included Age, Sex, HTN, DM, routine blood investigations, brain imaging, lipid profile, and others when required.TG/HDL-C ratio was categorized into two groups as <2 and >2 and correlated with the severity of stroke. Results: Out of 100 patients with ischemic stroke, majority of the patients (60%) were < 60 years of age, predominantly male (58%). Hypertension, DM, CAD, Smoking and alcoholism were the significantly associated with the severity of the stroke (p<0.05). Serum triglycerides level and highTG/HDL-C ratio (>2) were significantly associated with the severe stroke (p<0.05).  Conclusion: Hypertensions, Diabetes, dyslipidemia, smoking, alcohol, all are significantly associated with the severity of stroke. Serum triglycerides are raised in severe stroke patients than moderate stroke patients significantly.TG/HDL-C ratio is also related to the severity of stroke significantly.