European Journal of Cardiovascular Medicine

Background: The prevalence of cervical cancer is increasing day by day. One of the best methods to prevent it is vaccination by HPV (Human Papilloma Virus) vaccine. Now a day’s more and more females are coming forward to take HPV vaccine. Sero-prevalence is one of the best methods to assess disease burden in the community Objectives: 1.  To study sero-prevalence of HPV in adolescent girls.  2. To study association of seroprevalence of HPV with HPV vaccination.  Method:  A community based cross sectional study was performed to assess the sero-prevalence of HPV at two private schools in suburban areas of Hyderabad, Telangana, in April 2022 to September 2022. Blood samples from 100 adolescent girls were collected & analysed for HPV specific antibodies by ELISA. Results:  The sero-prevalence for HPV in the study group was low. There was a statistically significant HPV sero-positivity in all girls receiving HPV (<0.05). An association of sero-prevalence with age was analysed. There was no statistically significant association between age & HPV antibodies (p>0.05 Conclusion:  The prevalence of HPV infection among adolescent girls is low and it is strongly associated with HPV vaccination.