European Journal of Cardiovascular Medicine

Background: Persistent inflammation of the middle ear and mastoid cavity that manifests as recurrent ear discharge or otorrhoea due to a tympanic membrane perforation is known as chronic suppurative otitis media [1]. Objectives:  1) To categorize active chronic suppurative otitis media into tubotympanic and atticoantral disease. 2) To find out microbiological organisms responsible for both these categories (tubotympanic and atticoantral) and their sensitive drugs by culture and sensitivity report. Material & Methods: Study Design: Prospective Hospital based observational study. Study area: Department of E.N.T, Narayana Medical College and Hospital, Nellore, Andhra Pradesh. Study Period: June 2021 – May 2022.   Study population: Patients with CSOM of all age groups and both sexes attending the Narayana Medical College and Hospital, were selected randomly for the study. Sample size: study consisted a total of 50 cases. Sampling method: Simple random method. Results: Majority of pseudomonas infection showed mucopurulant type of discharge (50%) followed by S. aureus (33.33%). Purulent discharge was common in Pseudomonas (37.5%) and S. Aureus (37.5%). Mucoid discharge was common in Klebsiella (16.67%) followed by pseudomonas (27.78%) infection. It is interesting to know that 100% of no growth had mucoid discharge. Chi square was used to find the association between bacteria and discharge; and it was found not significant. Conclusion:  Out of 50 cases, 56 ears were examined, 51 pathogenic organisms were isolated. Only aerobic bacteria were isolated in the present series. P. aeruginosa was the most common organism isolated 23 (41.07%), followed by S. aureus 15 (26.79%), Klebsiella 5 (8.93%), E. coli 3 (5.36%), Proteus 3 (5.3%), Acinetobacter 1 (1.79%). No growth was found in 5 (8.93%) and commensal was found in 1 (1.8%) of discharge. Cf was the most effective antibiotic followed by Ak, G, Ce. In both TTD, AAD, no anaerobic organisms were cultured.