European Journal of Cardiovascular Medicine

Background and objectives: The present study evaluates the effect of essential oils of Rosmarinus officinalis and Populus alba on experimentally cutaneous heat-induced burn injury in rat.Materials and Methods: For this purpose, the acute toxicity test was carried out on Wistar rats that received intraperitoneally gradual doses (0.5to 7 ml /Kg) of the both essential oils. Then, Second-degree burn wounds were induced in five groups (N=5 in each). The percentage of wound healing were assessed on 5, 10, 15, 20 and 25 days. In the other hand, wound surface was monitored and photographed during the period of treatment. Results and Conclusion: The essential oil of Populus alba and even Rosmarinus officinalis have no acute toxicity in rats.