European Journal of Cardiovascular Medicine

Introduction: Angioedema (AE) is a reason for emergency care when it is severe. Care is difficult when the diagnostic is not known before the attack: Mast Cell (MC) or Bradykinin (BK) mediated. One is very common but often benign, the other rare but potentially fatal. The French national reference center of AE (CREAK) provides emergency physicians with a hotline and a guideline to help them manage their patients. Objective: This study aimed to describe the clinical features of AE episodes prompting a call on the CREAK hotline and classify patients depending on the suspected cause of the AE. Methods: It’s a retrospective study between March and August 2018. Each physician calling on the CREAK hotline was asked to fill a clinical description form for the AE emergency. Known patients of CREAK were excluded.