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Research Article | Volume 15 Issue 9 (September, 2025) | Pages 487 - 489
Point-of-Care Ultrasound versus Auscultation for Confirmation of Endotracheal Tube Placement: A Double-Blinded Prospective Study
 ,
 ,
1
Anaesthesiology, Senior Resident, SGRR IM & HS, Dehradun, Uttarakhand, India
2
Anaesthesiology, Professor, SGRR IM & HS, Dehradun, Uttarakhand, India
3
3Anaesthesiology, Professor, SGRR IM & HS, Dehradun, Uttarakhand, India.
Under a Creative Commons license
Open Access
Received
Aug. 20, 2025
Revised
Sept. 1, 2025
Accepted
Sept. 6, 2025
Published
Sept. 17, 2025
Abstract

Background: Accurate confirmation of endotracheal tube (ETT) placement is vital during anaesthesia and emergency airway management. Conventional auscultation has limited sensitivity, whereas point-of-care ultrasound (POCUS) has emerged as a promising alternative. Objective: To compare the diagnostic accuracy of POCUS and auscultation in confirming ETT placement. Methods: Ninety ASA I–II patients undergoing elective surgery under general anaesthesia were randomised into three groups (trachea, right main bronchus, left main bronchus). Independent blinded anaesthesiologists performed intubation, fibreoptic confirmation, auscultation, and ultrasound examinations. Diagnostic indices were calculated against fibreoptic bronchoscopy (gold standard). Results: Auscultation achieved sensitivity 68.8%, specificity 87.8%, and accuracy 84.7%. POCUS demonstrated sensitivity 92.5%, specificity 95.3%, and accuracy 94.7%. Haemodynamics and oxygen saturation remained stable, while EtCO₂ and airway pressures increased significantly with endobronchial intubations. Conclusion: POCUS is more accurate than auscultation for confirming ETT placement. It is a rapid, reliable, and non-invasive bedside tool with potential to complement or replace auscultation in clinical practice.

Keywords
INTRODUCTION

Endotracheal intubation is routinely performed in anaesthesia, intensive care, and emergency medicine. Misplacement of the ETT into the oesophagus or bronchus can cause hypoxemia, atelectasis, or barotrauma, making rapid confirmation essential. Auscultation has traditionally been recommended but is limited by poor sensitivity, especially in noisy environments or with inexperienced practitioners. Point-of-care ultrasound (POCUS) offers dynamic, real-time airway assessment, with early studies suggesting high diagnostic accuracy. This study compared the diagnostic performance of POCUS and auscultation against fiberoptic bronchoscopy for confirming ETT position.

MATERIALS AND METHODS

Design: Prospective, double-blinded, randomized controlled trial

Setting: Tertiary care hospital, Dehradun, India
Sample: 90 ASA I–II adult patients (20–60 years), elective surgeries under general anaesthesia

 

Exclusion: Obesity, lung disease, difficult airway, pregnancy, or refusal to consent

Procedure: Patients randomized into three groups (ETT in trachea, right main bronchus, left main bronchus). Fiberoptic confirmation served as gold standard. Five-point auscultation performed by blinded anaesthesiologist. POCUS examination (tracheal dilation and pleural sliding signs) performed by another blinded anaesthesiologist.


Outcomes: Diagnostic accuracy of each method. Secondary outcomes included haemodynamics, EtCO₂, and peak airway pressures.


Statistical Analysis: Chi-square/Fisher’s exact test, unpaired t-test, sensitivity/specificity/PPV/NPV, Kappa statistics. p < 0.05 considered significant.

RESULTS

Table .1 Changes in EtCO₂ and Peak Airway Pressure Pre vs Post Intubation

Parameter

Tracheal Group

Right Main Bronchus Group

Left Main Bronchus Group

p-value

EtCO₂ (mmHg, mean ± SD)

35.2 ± 4.1

44.5 ± 5.2

45.1 ± 4.8

<0.001

Airway Pressure (cmH₂O)

18.3 ± 2.5

28.7 ± 3.2

29.1 ± 3.5

<0.001

Table 2. Diagnostic Accuracy of Auscultation vs POCUS Compared with Fibreoptic Bronchoscopy

Method

Sensitivity (%)

Specificity (%)

Accuracy (%)

PPV (%)

NPV (%)

Kappa (κ)

Auscultation

68.8

87.8

84.7

78.3

82.1

0.62

POCUS

92.5

95.3

94.7

93.8

94.1

0.89

 

Table 3. Baseline Demographic and Clinical Characteristics of Patients (n = 90)

Variable

Tracheal Group (n=30)

Right Main Bronchus Group (n=30)

Left Main Bronchus Group (n=30)

p-value

Age (years, mean ± SD)

38.2 ± 10.5

39.1 ± 9.8

37.4 ± 11.2

0.72

Gender (M/F)

18/12

20/10

19/11

0.83

ASA I/II (%)

70/30

66/34

72/28

0.89

Weight (kg, mean ± SD)

62.4 ± 8.7

61.9 ± 9.3

63.1 ± 7.9

0.91

 

Figure 1: Diagnostic performance of auscultation vs ultrasound (POCUS).

Figure 1: Diagnostic performance of auscultation vs ultrasound (POCUS).

Figure 2: Change in EtCO₂ pre vs post intubation.

Figure 3: Change in peak airway pressure pre vs post intubation.

DISCUSSION

This study confirms that POCUS significantly outperforms auscultation in detecting ETT placement, aligning with previous literature. Auscultation, although widely practised, is limited by poor sensitivity and dependence on operator expertise. In contrast, POCUS allows real-time airway assessment, is unaffected by environmental noise, and does not require interruption of chest compressions during CPR. The PLUS examination (tracheal dilation and pleural sliding) achieved high diagnostic accuracy (94.7%), supporting its role in routine airway confirmation. Limitations include the single-centre design and exclusion of obese and emergency cases. Further multicentre trials are warranted to validate its utility in critical and prehospital scenarios.

CONCLUSION

POCUS provides a rapid, reliable, and accurate method for confirming ETT placement. It outperforms auscultation and should be considered as an adjunct, or even a replacement, in perioperative and critical care airway management. Broader adoption of POCUS may improve patient safety, particularly in high-risk or resource-constrained settings.

REFERENCES
  1. Ramsingh D, Rinehart J, Kain Z, et al. Ultrasound versus auscultation of endotracheal tube position: A prospective, randomized, blinded trial. Anesth Analg. 2016;122(2):543-548.
  2. Hu WC, Wang CY, Lin TY, et al. Point-of-care ultrasound for double-lumen tube position confirmation: A prospective study. J Cardiothorac Vasc Anesth. 2018;32(2):856-862.
  3. Parab SY, Divatia JV, Chogle A. Tracheal ultrasonography for confirming endotracheal tube placement: A systematic review and meta-analysis. Indian J Crit Care Med. 2019;23(5):235-244.
  4. Kad N, Bhardwaj N, Singh S. Confirmation of endotracheal tube placement by ultrasonography versus auscultation: A prospective study. J Anaesthesiol Clin Pharmacol. 2018;34(2):223-227.
  5. Kuppusamy A, Balakrishnan S, Reddy PR, et al. Real-time ultrasonography versus capnography for confirming endotracheal tube placement. Indian J Anaesth. 2022;66(4):300-306.
  6. Sitzwohl C, Langheinrich A, Weinstabl C, et al. Endobronchial intubation detected by auscultation and observation: A randomized trial. Br J Anaesth. 2010;104(3):337-343.
  7. Khosla R, Khosla S, Murali N. Bedside ultrasound versus clinical methods for confirmation of endotracheal tube placement in critical care. Indian J Crit Care Med. 2016;20(9):593-596.
  8. Chowdhury AR, Sinha A, Mehra R, et al. Ultrasound versus capnography and chest auscultation for confirmation of endotracheal intubation in novice trainees. Indian J Anaesth. 2020;64(3):232-238.
  9. Ariff S, Karim M, Haque A, et al. Point-of-care ultrasound versus standard methods for neonatal intubation confirmation: A cross-sectional study. Arch Dis Child Fetal Neonatal Ed. 2022;107(3):330-336.
  10. Mekewar S, Rathi V, Patil K. Ultrasound versus capnography with auscultation for endotracheal tube confirmation: A comparative study. J Anaesthesiol Clin Pharmacol. 2022;38(2):212-217.
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