European Journal of Cardiovascular Medicine

Background: Psoriasis is an immune-mediated inflammatory disease, where a sustained inflammatory state causes comorbidities such as, metabolic syndrome (MS), psoriatic arthritis and cardiovascular disease. Aims: 1) To find out the prevalence of metabolic syndrome in patients of chronic plaque psoriasis. 2) To study the association of metabolic syndrome with severity of psoriasis and duration of psoriasis. Methods: It was an observational cross-sectional study for a period of one year (February 2021 to January 2022) in the Department of Dermatology, Tripura Medical College & Dr BRAM Teaching Hospital, Agartala. All diagnosed cases of psoriasis patients attending the Dermatology department enrolled after obtaining informed consent and prior Institutional Ethics Committee (IEC) permission. Total 90 patients were included using purposive sampling technique. Results: Present study found; 30 patients (40%) were having metabolic syndrome with mean age of study participants was 38.28 ± 10.29 years. Prevalence of metabolic syndrome was higher in severe psoriasis (59.5%) group compared to moderate (27.9%) and mild psoriasis (20%) group which was statistically significant (p value < 0.05). We also found that prevalence of metabolic syndrome was higher in patients who have psoriasis for longer duration (>3 years) which was statistically significant (p value < 0.05). Metabolic syndrome is seen frequently in patients of psoriasis specially those who has a longer disease course with higher PASI score. Conclusion: Prevalence of metabolic syndrome was higher in severe psoriasis patients. Patients with psoriasis should be regularly screened and advised lifestyle modification such as healthy diet, physical exercise, and stress reduction to reduce the incidence of metabolic syndrome.