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Research Article | Volume 15 Issue 6 (June, 2025) | Pages 82 - 87
Heart Disease Deaths in Sagar Bundelkhand Region, an Autopsy Based Retrospective Study
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1
PG-Resident, Bundelkhand medical College Sagar (M.P.)-470002
2
Professor & HOD, Bundelkhand medical College Sagar (M.P.)-470002
3
Assistant professor, Bundelkhand medical College Sagar (M.P.)-470002
4
Demonstrator MD, FMT) department of forensic medicine and toxicology, Bundelkhand medical College Sagar (M.P.)-470002
5
PG-Resident, NSC GMC Khandwa
Under a Creative Commons license
Open Access
Received
April 25, 2025
Revised
May 10, 2025
Accepted
May 26, 2025
Published
June 9, 2025
Abstract

Background: AIM: To retrospectively find the different pathologies of heart disease in the cases examined at Mortuary of Bundelkhand Medical College, Sagar, M.P and district hospital Sagar M.P. Objectives: To find the incidence of heart disease in different age groups and different sex To find the incidence of different pathologies of heart   Materials And Methods: 2250 autopsies were performed during the time period of July. 2023 to Dec. 2024 out of that 83 cases of cardiac deaths were found. Deaths due to non-cardiac causes, such as trauma were excluded.  Study design – Cross sectional study, retrospective, Study area – Sagar Bundelkhand region, Study population – All autopsy cases which came to Bundelkhand medical college mortuary  and district hospital Sagar during the time period of July 2023 – December 2024.  Results: Out of total 2250 autopsies conducted  83 cases of heart disease deaths were recorded. Among them 81.93% were due to coronary artery disease (CAD). 59.04% cases had cardiomegaly and heart weight was more (>420 gms) in 59.04 % cases. Among 83 cases of cardiac deaths 92 % victims were males and 8 % were females. The peak incidence of heart diseases was found to be in the age group of 40-49 yrs (27.71 %) followed by 50-59 yrs (26.51%). Least incidence were found in the age group below 19.  Conclusion: Most of the heart disease deaths examined were due to coronary artery disease (CAD). Majority of victims were males. Hence this data shows us the quintessential requirement of intervention in the prevention of heart diseases 

Keywords
INTRODUCTION

Heart diseases comprise the most prevalent serious disorders in industrialized nations and are a rapidly growing problem in developing nations1 Heart disease is now the most common cause of death worldwide. Before 1900, infectious diseases and malnutrition were the most common causes, and heart disease was responsible for <10% of all deaths.  In 2017, heart disease accounted for 17.8 million deaths worldwide (32%), with the same rate now occurring in high, low and middle-income countries1. India has one of the highest burdens of heart disease worldwide. The annual number of deaths from heart disease in India is projected to rise from 2.26 million (1990) to 4.77 million (2020)(2) Coronary artery disease(CAD) prevalence rates in India have been estimated over the past several decades and have ranged from 1.6% to 7.4% in rural populations and from 1% to 13.2% in urban populations3

 

Atherosclerosis is primarily a disease of aorta, carotid , iliac and coronary arteries.

Recent advances in the field of modern medicine with the effective treatment life expectancy has been increased and an improvement in the quality of life but despite these achievements, the prevalence of coronary artery disease (CAD) still remains high4.

 

Aim and Objectives

Aim 

  • To retrospectively find the different pathologies of heart disease in the cases examined at Mortuary of Bundelkhand Medical College, Sagar, M.P and district hospital Sagar, M.P

 

Objectives

To find the incidence of heart disease in different age groups and different sex

To find the incidence of different pathologies of heart

MATERIALS AND METHODS

2250 autopsies were performed during the time period of July 2023 to December 2024 out of that 83 cases of cardiac deaths were found. Deaths due to non-cardiac causes, such as trauma were excluded

 

RESULTS
  • Sex
  • Age
  • Heart weight
  • Cardiomegaly
  • Types of pathology
  • 2250 autopsies were performed during the time period of July 2023 to December 2024 out of that 83 cases of cardiac deaths were found.
  • The cases in study were divided into different age groups according to the age and sex.
  • 76 (92%) victims were males and 07 (8% )were females
  • Most of the deceased from both sexes belonged to 40-49 yrs (27.71%) followed by 50-59 yrs (26.51%). Least incidence were found in the age group below 19 years and >80 years.

Among 83 cases of cardiac deaths (92%) victims were males and (8%) were females

Age

Below 20 years and above 80 years 2 cases were found, who died from heart disease

Heart weight

Any person with a heart in excess of 420gm is at risk of sudden death5 . Maximum heart weight recorded in 1 case was 900gms

DISCUSSION

There is considerable increase in the number of deaths due to coronary atherosclerosis in India and this number is probably expected to increase in the coming decades if not controlled6. The most concern is the early age of CHD deaths in the developing countries as compared to the developed countries, which will definitely lame the major work force of our nation7

 

 

Comparison with previous studies Males are more affected than females

 

In the studies of Sudha et al8. Virmani et al9. and Stary. et al10. CAD develop quite early in life starting from age 20 years onwards. In our study incidence of CAD was found to be 81.93 % which was comparable with the frequency given by Dr. Sunil et al. (49.02%)11,Yazdi et al. (40%)12 and Golshahi et al. (28.9%)13. Likely the acquisition of several risk factors such as tobacco consumption, lack of physical activity, stress, unhealthy diet, and obesity.

CONCLUSION

Coronary artery disease was the major contributory cause of heart disease deaths and most numbers of deaths were reported in the age group 40-49 followed by 50-59 years with male to female ratio 10:1 .

Hence this data shows us the quintessential requirement of intervention in the prevention of heart diseases

REFERENCES

1.       Harrison’s  principles of  internal medicine by McGraw Hill LLC 21st ed .2022; 238:1810.

2.       Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study. Lancet. 1997;349:1498–504. [PubMed] [Google Scholar]

3.       Gupta R, Joshi P, Mohan V, Reddy KS, Yusuf S. Epidemiology and causation of coronary heart disease and stroke in India. Heart. 2008;94:16–26. [PubMed] [Google Scholar]

4.       NCMH Background Papers: Burden of Disease in India. National Commission on Macroeconomics and Health, Government of India 2005

5.       Dr. K.S Narayan Reddy and Dr. O.P. Murty the essentials of forensic medicine & toxicology 34th ed. 2017;139.

6.       Curtiss LK. Reversing Atherosclerosis? N Engl J Med 2009; 360:1144-6.

7.       Noeman A, Ahmad N, Azhar M. Coronary artery disease in young: Faulty life style or heredofamilial or both. Annals 2007;13:162-4.

8.       Sudha ML, Sundaram S, Purushothaman KR, Kumar PS, Prathiba D. Coronary atherosclerosis in sudden cardiac death: An autopsy study. Indian J Pathol Microbiol 2009;52(4):486-9.

9.       Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM. Lessons from sudden coronary death-Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM. Lessons from sudden coronary death-A comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2000;20:1262-75.

10.    Golshahi J, Rojabi P, Golshahi F. Frequency of atherosclerotic lesions in coronary arteries of autopsy specimens in Isfahan forensic medicine center. J Res Med 2005;1(10):16-9.

11.    Dr. Sunil Jaiswal, 2Dr. Priyanka Kiyawat, 3Dr. Nidhi Sharma, 4Dr. Ashok Panchonia, 5Dr. Priyanka Verma, 6Dr. Tushar Mourya Status of coronary atherosclerosis in population of MP: An autopsy based study EJMCM_vol.8 2021;4:971.

12.    Yazdi SA, Rezaei A, Azari JB, Hejazi A, Shakeri MT, Shahri MK. Prevalence of atherosclerotic plaques in autopsy cases with non-cardiac death. Iran J Pathol 2009;4:101-4.

13.    Monika Garg, Akash Deep Agarwal, Sant Prakash Kataria. Coronary Atherosclerosis and Myocardial Infarction an Autopsy Study. J Indian Acad Forensic Med 2011;33(1):39-42

 

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