European Journal of Cardiovascular Medicine

Chronic alcohol abuse remains a pressing global health concern, with far-reaching implications for both biochemical markers and cardiac function. This cross-sectional study aims to comprehensively assess the impact of chronic alcohol abuse on these parameters. Methods: We conducted a study involving 200 participants to investigate the interplay between demographics, alcohol consumption patterns, biochemical markers, and cardiac function. Data were collected through questionnaires, biochemical assays, and echocardiographic assessments. Results: Demographics and Alcohol Consumption Patterns: Our finding revealed a predominantly middle-aged cohort, with a higher prevalence of males (60%) and an average age of 45 years. Participants demonstrated chronic alcohol abuse, with an average duration of 18 years and daily alcohol intake significantly exceeding recommended limits.In a cohort of 200 chronic alcohol users, our study identified significant elevations in biochemical markers: GGT (70 ± 20 U/L), BNP (300 ± 100 pg/mL), and NT-proBNP (900 ± 300 pg/mL), all surpassing normal ranges, indicative of liver and cardiac stress. Echocardiographic data revealed increased ventricular dilation (35 ± 10%) and reduced ejection fraction (50 ± 8%), highlighting cardiac dysfunction. Conclusion:  Comparative analysis showed more pronounced abnormalities in heavy drinkers versus moderate drinkers, emphasizing the dose-dependent impact of alcohol on health.